An appraisal of post-irradiation metabolic changes in toad liver (Bufo melanostictus).
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2002-10-16
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Whole body 60Co gamma irradiation of B . melanostictus with two sublethal doses of 3.5 and 7 Gy resulted in a significant increase (P < 0.001) in total lipid (hyperlipidemia), cholesterol content (hypercholesterolemia) and total free amino acid content, and significant decrease (P < 0.001) in total protein content in the liver tissues on post-irradiation day (PID) 1, 5 and 10 as compared to controls. The ratio of total lipid to cholesterol showed a gradual declining trend by PID-10 in the treated groups as compared to controls. However, it was more pronounced in the 7 Gy treated group. An observation on the ratio of total protein to total free amino acid content also showed a similar declining trend by PID-10 in both the treated groups as compared to controls.
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Mishra J, Mittra A. An appraisal of post-irradiation metabolic changes in toad liver (Bufo melanostictus). Indian Journal of Experimental Biology. 2002 Oct; 40(10): 1198-201