Effect of steroidal fraction of seeds of Abrus precatorius Linn. on rat testis.
No Thumbnail Available
Date
1990-08-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Dose-dependent degenerative changes in the testicular weights, sperm count, later stages of spermatogenesis and Leydig cells are observed in testis of rats treated with steroidal fraction of seeds of A. precatorius. These are correlated with the dose-dependent decrease in the enzyme activity of 3 alpha, 3 beta, 17 beta-hydroxysteroid dehydrogenases, glucose-6-phosphate dehydrogenase, sorbitol dehydrogenase and leucine aminopeptidase. The steroidal fraction may also exert its influence indirectly at the pituitary level by a feedback mechanism, leading to decrease in production and release of testosterone which results in significant alterations in the testis.
Description
Keywords
Citation
Sinha S, Mathur RS. Effect of steroidal fraction of seeds of Abrus precatorius Linn. on rat testis. Indian Journal of Experimental Biology. 1990 Aug; 28(8): 752-6