Effect of mild hyperlipidaemia on testicular cell population dynamics in albino rats.

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Date
1999-04-21
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Abstract
Mild hyperlipidaemia induced by cholesterol feeding to male rats altered testicular histology. The sperm motility and density were significantly reduced in cauda epididymides and testes in mild hyperlipidaemic rats. The testicular cell population i.e. spermatocytes (primary and secondary) and spermatids were significantly reduced (P < or = 0.01 to 0.001). However, the number of degenerating Leydig cells (interstitial cells) were increased significantly (P < or = 0.001). Serum biochemistry reveals significant rise in cholesterol and triglycerides. It is concluded that cholesterol feeding caused inhibition of spermato genesis.
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Purohit A, Daradka HM. Effect of mild hyperlipidaemia on testicular cell population dynamics in albino rats. Indian Journal of Experimental Biology. 1999 Apr; 37(4): 396-8
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https://imsear.searo.who.int/handle/123456789/59028
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Indian Journal of Experimental Biology