Effect of short-term treatment of eugenol on the seminal vesicles of adult albino rats.

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1998-12-27
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The structure and biochemical content of adult albino rat seminal vesicles, were studied, after administration of two different doses of eugenol for 10 days (0.2 and 0.3 mg/kg/day, i.m.). Marked decreases in the concentrations of nucleic acids, fructose and total protein as well as RNA/DNA ratio (61%) and protein/DNA ratio (27%) were observed. A remarkable increase in phospholipid concentration was noted with a corresponding decrease in neutral lipids. Histologically, eugenol treated animals showed degeneration of the secretory columnar cells and well developed myofibrillar connective tissues when compared to control animals.
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Vanithakumari G, Sampathraj R, Selvaraj M, Thangamani R. Effect of short-term treatment of eugenol on the seminal vesicles of adult albino rats. Indian Journal of Experimental Biology. 1998 Dec; 36(12): 1240-4