Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn.
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2002-08-25
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A non-toxic dose of abrin, (1.25 microg/kg body wt) consecutively for five days in normal mice stimulated specific humoral responses. A noticeable increase was observed in total leucocyte count, lymphocytosis, weights of spleen and thymus, circulating antibody titre, antibody forming cells, bone marrow cellularity and alpha-esterase positive bone marrow cells. The results suggest that abrin can potentiate the humoral immune response of the host.
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Ramnath V, Kuttan G, Kuttan R. Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn. Indian Journal of Experimental Biology. 2002 Aug; 40(8): 910-3