Cervix tumour cell line established from tumour after long term passages as heterotransplant in nude mice.

Pal, A K; Pratap, M; Mitra, A B

Cervix tumour cell line established from tumour after long term passages as heterotransplant in nude mice.

Date

1992-07-01

Authors

Pal, A K

Pratap, M

Mitra, A B

Abstract

One human cancer of the uterine cervix xenograft was established in tissue culture only after repeated passages in nude mice suggesting that with the repeated passages in nude mice, tumour cells acquire some properties which allow them to grow in vitro. Attempts to establish cell line tumours from earlier passages were not successful. The established cell line is tumourigenic. On inoculation of cultured cells in nude mice tumour take was found to be 100%. Karyotypic analysis revealed human origin.

Citation

Pal AK, Pratap M, Mitra AB. Cervix tumour cell line established from tumour after long term passages as heterotransplant in nude mice. Indian Journal of Experimental Biology. 1992 Jul; 30(7): 655-6