Methyl parathion induced alterations in monoaminergic system of developing rat pups.

No Thumbnail Available
Date
2001-03-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Methyl parathion induced alterations in the level of monoamines, viz. norepinephrine, dopamine and serotonin were studied in discrete regions of developing central nervous system of rat pups. A significant decrease in the level of monoamines noticed in methyl parathion toxicosis may be related to the altered neuronal activity and inefficiency, leading to depression and impairment in various behavioural activities. In contrast to AChE inhibition, monoamine oxidase (MAO) activity showed an increasing trend and it could cause deamination of catecholamines and accumulation of its metabolites. This suggests that an increased AChE inhibition may indirectly stimulate MAO activity in developing rat pups exposed to methyl parathion.
Description
Keywords
Citation
Mahaboob Basha P, Begum S, Nayeemunnisa . Methyl parathion induced alterations in monoaminergic system of developing rat pups. Indian Journal of Experimental Biology. 2001 Mar; 39(3): 276-9
URI
https://imsear.searo.who.int/handle/123456789/56599
Collections
Indian Journal of Experimental Biology