Sub-clinical infection with Mycobacterium leprae in household contacts of leprosy.

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1990-07-01
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870 household contacts of leprosy patients were examined for sub-clinical infection with M. leprae by smear (skin and nasal), lepromin and FLA-ABS tests. 0.6%, 3.3%, 71.5% and 14.4% of the contacts were found to be positive for skin smear, nasal smear, lepromin and FLA-ABS tests respectively. An analysis of the results revealed that 4% of the lepromin positive contacts and 3.6% of the lepromin negative contacts were positive to both FLA-ABS and skin or nasal smear.
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Bhatia VN, Dhandayuthapani S, Ananthan D, Rajendran M, Vasanth B, Jayasingh K, Kumar CH. Sub-clinical infection with Mycobacterium leprae in household contacts of leprosy. Indian Journal of Leprosy. 1990 Jul-Sep; 62(3): 296-304