Relative susceptibility of six continuous cell lines for cultivation of chlamydia trachomatis strains.
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Date
2004-07-24
Authors
Malathi, J
Shyamala, G
Madhavan, H N
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Abstract
Since susceptibility of a cell line is an important factor for cultivation of Chlamydia trachomatis, McCoy, HeLa, BHK-21, HEp-2, Vero and A549 cell lines were tested for this characteristic. These were inoculated with 150 infection-forming units (IFU) of C. trachomatis A, B, Ba and C serovars. Growth was graded according to the number of IFUs per microscopic field (100X). A549-cell line was not susceptible to infection by any of the serovars. The growth of C. trachomatis was good to very good in McCoy and HeLa cell lines. Vero, BHK-21 and HEp-2 cell lines varied considerably in the susceptibility to infection.
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Malathi J, Shyamala G, Madhavan HN. Relative susceptibility of six continuous cell lines for cultivation of chlamydia trachomatis strains. Indian Journal of Medical Microbiology. 2004 Jul-Sep; 22(3): 169-71