Evaluation of the effectiveness of peracetic acid in the sterilization of dental equipment.
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2008-04-01
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Abstract
PURPOSE: To evaluate the effectiveness of peracetic acid in the microbiological sterilisation of dental materials.
METHODS: Peracetic acid solution was evaluated at concentrations of 800, 1500 and 2500 ppm. At these concentrations, it was determined whether peracetic acid caused corrosion to dental instruments and induced cellular mutagenicity and cytotoxicity. In addition, the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC), agar diffusion and diffusion by well method, were also verified.
RESULTS: The corrosion rate, calculated from potentiodynamic assays was 10(-6) cm/year, indicating that the product does not damage equipment. The sterilisation capacity of peracetic acid at 2500 ppm was the best. The comet assay indicated genotoxic activity at 2500 ppm.
CONCLUSIONS: This study demonstrated the effectiveness of peracetic acid for sterilizing dental equipment, providing another alternative for the prevention of infections in clinics.
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Ceretta R, Paula MM, Angioletto E, Méier MM, Mitellstädt FG, Pich CT, Junior SA, Angioletto E. Evaluation of the effectiveness of peracetic acid in the sterilization of dental equipment. Indian Journal of Medical Microbiology. 2008 Apr-Jun; 26(2): 117-22