Fatal haemophagocytic syndrome and hepatitis associated with visceral leishmaniasis.

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2007-10-19
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Abstract
Haemophagocytic syndrome (HPS) secondary to infections occurs due to excessive, non-malignant proliferation of histiocytes, with resultant haemophagocytosis. The syndrome is essentially treatable, provided timely etiological diagnosis is achieved. In this report, we present a rare case of a child who hailed from Uttaranchal and presented with severe hepatitis. Bone marrow examination revealed an unexpected diagnosis of HPS secondary to visceral leishmaniasis. Despite initiating appropriate antileishmanial treatment, the child had a fatal outcome.
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Mathur P, Samantaray JC, Samanta P. Fatal haemophagocytic syndrome and hepatitis associated with visceral leishmaniasis. Indian Journal of Medical Microbiology. 2007 Oct; 25(4): 416-8