Meckel Gruber syndrome: occurrence in non-consanguineous marriages.

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Date
2004-03-17
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Abstract
Meckel Gruber syndrome is an uncommon, lethal, autosomal recessive disorder, associated consistently with polycystic kidneys, posterior encephalocoele and polydactly. We report three cases in non-consanguineous marriages, suggesting that the single gene defect occurs more commonly in non-consanguineous marriages than mutant genes associated with other autosomal recessive disorders that are usually related with consanguineous marriages. The usefulness of prenatal diagnosis is discussed.
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The Ceylon Medical Journal.
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de Silva MV, Senanayake H, Siriwardana KD. Meckel Gruber syndrome: occurrence in non-consanguineous marriages. The Ceylon Medical Journal. 2004 Mar; 49(1): 30-1
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https://imsear.searo.who.int/handle/123456789/47389
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Ceylon Medical Journal