Effect of maternal deprivation on growth of Wistar rats in preweaning period.
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Date
2007-04-08
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Abstract
OBJECTIVE: The objective of this study was to observe the effect of maternal deprivation on somatic growth of wistar rat pups viz. Body weight, nose-rump length, tail length and head length.
MATERIALS AND METHOD: 5 days old 50 rat pups were studied dividing equally into control and experimental groups. Experimental group (N=25) of rats were maternally deprived 1-4 hours twice daily till the weaning period. Body weight and measurement of body parts were recorded at 4 days interval till 29th day. Recorded parameters were statistically analysed.
RESULT: The result of this study revealed that maternal deprivation stress produces significant effect in the body weight, nose-rump length and tail length from D9 till the study period whereas head length insignificantly affected.
CONCLUSION: MD stress has profound effects on somatic growth and found irreversible even after withdrawal for a period of 8 days.
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Kathmandu University Medical Journal.
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Dhungel S. Effect of maternal deprivation on growth of Wistar rats in preweaning period. Kathmandu University Medical Journal. 2007 Apr-Jun; 5(2): 210-4