Rapid detection of helicobacter pylori by endoscopic brush cytology and comparison with histopathology.
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Date
2007-07-08
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Abstract
OBJECTIVES: The main objective of this study was to assess antral brush cytology as an alternate approach for the diagnosis of H. pylori infection as compared to histopathology.
METHODS: 75 cases with diagnosis of antral gastritis underwent endoscopic antral biopsy as well as antral brushing cytology was included irrespective of age and sex. Cytological slides were stained with Giemsa stain & biopsy slides were stained with H&E and Giemsa stain. Correlation was done between cytological smear slides and biopsy slides.
RESULTS: Among 75 cases, H. pylori were positive in 55 (73.4%) cases of biopsy specimens while in brush cytology it was positive in 48 (64%) cases. In 45 (60%) of 75 cases, H. pylori was seen in both biopsy and brush cytology.
CONCLUSION: Endoscopic brush cytology provides an accurate, inexpensive and easy technique in the rapid detection of H.pylori infection.
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Kathmandu University Medical Journal.
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Akhter J, Shrestha HG. Rapid detection of helicobacter pylori by endoscopic brush cytology and comparison with histopathology. Kathmandu University Medical Journal. 2007 Jul-Sep; 5(3): 387-90