Malignant peripheral nerve sheath tumor of breast in patient without Von Recklinghausen's neurofibromatosis: a case report.

Thanapaisal, C; Koonmee, S; Siritunyaporn, S

Malignant peripheral nerve sheath tumor of breast in patient without Von Recklinghausen's neurofibromatosis: a case report.

Date

2006-03-16

Authors

Thanapaisal, C

Koonmee, S

Siritunyaporn, S

Abstract

Malignant peripheral nerve sheath tumor (MPNST) of the breast without Von Recklinghausen's neurofibromatosis (VRN) is extremely rare. The authors report a 19 year-old woman who presented with a 12 month history of a painless mass of the left breast. Tissue biopsy was performed. The histologic diagnosis was made with immunohistochemical study in which the tumor showed positivity of vimentin, S-100 protein, neuron-specific protein(NSE), neurofilament protein(NF) and glial fibrillary acidic protein(GFAP). The patient was referred for radiation therapy after simple mastectomy.

Description

Chotmaihet Thangphaet.

Citation

Thanapaisal C, Koonmee S, Siritunyaporn S. Malignant peripheral nerve sheath tumor of breast in patient without Von Recklinghausen's neurofibromatosis: a case report. Journal of the Medical Association of Thailand. 2006 Mar; 89(3): 377-9