Correlation of 4- and 24-hour urine protein in women with initially diagnosed hypertensive disorders in pregnancy.

Wongkitisophon, Kitti; Phupong, Vorapong; Yamasmit, Waralak; Pansin, Pongsak; Tannirandorn, Yuen; Charoenvidhya, Dhiraphongs

Correlation of 4- and 24-hour urine protein in women with initially diagnosed hypertensive disorders in pregnancy.

Date

2003-06-20

Authors

Wongkitisophon, Kitti

Charoenvidhya, Dhiraphongs

Abstract

OBJECTIVE: To determine whether 4-hour urine protein value correlates with 24-hour urine protein value in women with hypertensive disorders in pregnancy. STUDY DESIGN: Cross-sectional study was performed in 38 in-patient pregnant women who were initially diagnosed as having hypertensive disorders in pregnancy. Urine samples were collected within 24 hours in 2 successive periods: the first 4-hour and the next 20-hour urine, in separate containers. The urine volume, urine protein and creatinine concentrations were thus separately measured. The 4- and 24-hour urine proteins were calculated and the correlation between both groups was determined by simple linear regression analysis. RESULTS: A total of 38 patients were recruited into the study, 26 had mild preeclampsia, 5 had severe preeclampsia, and 7 had superimposed preeclampsia. The result of the 4-hour urine protein was found to correlate with those of the 24-hour urine protein for patients with hypertensive disorders in pregnancy (p < 0.001). CONCLUSION: Total protein values of 4-hour samples positively correlated with values of 24-hour samples of patients with hypertensive disorders in pregnancy. This might be modified and used for urine protein collection in outpatients to improve the compliance.

Description

Chotmaihet Thangphaet.

Citation

Wongkitisophon K, Phupong V, Yamasmit W, Pansin P, Tannirandorn Y, Charoenvidhya D. Correlation of 4- and 24-hour urine protein in women with initially diagnosed hypertensive disorders in pregnancy. Journal of the Medical Association of Thailand. 2003 Jun; 86(6): 529-34