Comparison of efficacy of peptilose-base ORS (ORALNU) and WHO-ORS.
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Date
1993-10-01
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Abstract
We examined whether replacing glucose with Peptilose into standard ORS would be advantageous over WHO-ORS. A study was carried out on 134 diarrheal children with mild to moderate dehydration. They received either WHO-ORS or Peptilose-ORS by randomized selection. In only two cases in each group, diarrhea was caused by Vibrio cholerae non 0-1. Significant per cent weight gain was observed in patients with Peptilose-ORS compared to those treated with WHO-ORS (P = 0.046). The patients could voluntarily take a higher amount of Peptilose-ORS and had significantly less stool output in the combined mildly and moderately dehydrated patients. It is concluded that Peptilose-ORS is more advantageous and acceptable than the standard WHO glucose-ORS for treatment of non cholera and 2 cases of cholera dehydrating diarrhea in children.
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Chotmaihet Thangphaet.
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Citation
Simakachorn N, Pichaipat V, Ritthipornpisarn P, Kongkaew C, Ahmad S, Varavithya W. Comparison of efficacy of peptilose-base ORS (ORALNU) and WHO-ORS. Journal of the Medical Association of Thailand. 1993 Oct; 76 Suppl 2(): 42-8