Hemophagocytic syndrome in Dengue hemorrhagic fever with severe multiorgan complications.

Srichaikul, Tanomsri; Punyagupta, Sompone; Kanchanapoom, Termkiat; Chanokovat, Chow; Likittanasombat, Kanchit; Leelasiri, Apichai

Hemophagocytic syndrome in Dengue hemorrhagic fever with severe multiorgan complications.

Date

2008-01-05

Authors

Srichaikul, Tanomsri

Punyagupta, Sompone

Kanchanapoom, Termkiat

Chanokovat, Chow

Likittanasombat, Kanchit

Leelasiri, Apichai

Abstract

A 46 year old woman who presented with severe multiorgans involvement including liver brain, cardio-pulmonary failure, gastrointestinal bleeding, progressive cytopenia, DIC and hemophagocytic syndrome during the convalescent phase of Dengue type II has been successfully treated primarily with pulse methyl prednisolone and high dose intravenous immunoglobulin G. The authors believe that HPCS are not infrequently seen with high mortality and recommended early diagnosis and treatment with the regimen. This is the first complete report of hemophagocytic syndrome in adult dengue hemorrhagic fever in Thailand. The literature of HPCS in DHF was reviewed and discussed.

Description

Chotmaihet Thangphaet.

Citation

Srichaikul T, Punyagupta S, Kanchanapoom T, Chanokovat C, Likittanasombat K, Leelasiri A. Hemophagocytic syndrome in Dengue hemorrhagic fever with severe multiorgan complications. Journal of the Medical Association of Thailand. 2008 Jan; 91(1): 104-9