The development and validation of a diabetes risk score for high-risk Thai adults.

Keesukphan, Prasit; Chanprasertyothin, Suwannee; Ongphiphadhanakul, Boonsong; Puavilai, Gobchai

The development and validation of a diabetes risk score for high-risk Thai adults.

Date

2007-01-12

Authors

Keesukphan, Prasit

Chanprasertyothin, Suwannee

Ongphiphadhanakul, Boonsong

Puavilai, Gobchai

Abstract

OBJECTIVE: To develop a simple risk score to identify high-risk individuals for diabetes screening in Thailand. MATERIAL AND METHOD: The authors analyzed data from 75-g oral glucose tolerance tests performed in 159 males and 270 females, aged 48.4 +/- 10.9 years. RESULTS: The independent variables associated with diabetes included age (p < 0.001), BMI (p < 0.01) and known history of hypertension (HHT) (p < 0.01). The risk equation was Y = 3 age + 5 BMI + 50 HHT. At the cut-off Y value of 240, the sensitivity and specificity for having diabetes were 96.8% and 24.0%, respectively. The positive predictive value was 17.8% and the negative predictive value was 97.8%. Using the equation in a validation group comprising 1617 subjects, it was found that 560 (34.6%) diabetes screenings could be saved while 28 subjects (12.8%) with diabetes would be missed. CONCLUSION: The authors have developed a simple risk scoring method that should be helpful in decreasing the number of unnecessary screening and optimizing the costs associated with diabetes screening.

Description

Chotmaihet Thangphaet.

Citation

Keesukphan P, Chanprasertyothin S, Ongphiphadhanakul B, Puavilai G. The development and validation of a diabetes risk score for high-risk Thai adults. Journal of the Medical Association of Thailand. 2007 Jan; 90(1): 149-54