A case report of tumor-induced osteomalacia: eight year followed-up.

Ratanasuwan, Tanaporn; Chetsurakarn, Somchai; Ongphiphadhanakul, Boonsong; Damrongkitchaiporn, Somneok

A case report of tumor-induced osteomalacia: eight year followed-up.

Date

2008-12-13

Authors

Ratanasuwan, Tanaporn

Chetsurakarn, Somchai

Ongphiphadhanakul, Boonsong

Damrongkitchaiporn, Somneok

Abstract

Tumor-induced osteomalacia (TIO) is a rare but potentially curable disease. It is caused by excessive renal clearance ofphosphate induced by a substance secreted from the tumor Here, the authors report a Thai patient who presented with multiple pathologic fractures, low serum phosphorus, and low tubular maximum reabsorption of phosphorus/glomerular filtration rate (TmPO4/GFR). The clinical, biochemical and bone abnormalities improved 6 months after the surgery. Two years follow-up showed no recurrence of the disease. Physicians should be aware of this condition when encountering with adult onset osteomalacia.

Description

Chotmaihet Thangphaet.

Citation

Ratanasuwan T, Chetsurakarn S, Ongphiphadhanakul B, Damrongkitchaiporn S. A case report of tumor-induced osteomalacia: eight year followed-up. Journal of the Medical Association of Thailand. 2008 Dec; 91(12): 1900-2