Prevention of antibiotic-associated diarrhea in infants by probiotics.

Jirapinyo, Pipop; Densupsoontorn, Narumon; Thamonsiri, Nuchnoi; Wongarn, Renu

Prevention of antibiotic-associated diarrhea in infants by probiotics.

Date

2002-08-31

Authors

Jirapinyo, Pipop

Densupsoontorn, Narumon

Thamonsiri, Nuchnoi

Wongarn, Renu

Abstract

Probiotics administration has been claimed to prevent antibiotic-associated diarrhea. The investigators thus conducted a double blind, placebo controlled study of providing probiotics to infants and children with severe bacterial infections and receiving broad spechum antibiotics. The results of the study showed that the group receiving probiotics had fewer diarrheal episodes (37.5%) than the control group (80%), although the numbers were too small for statistical analysis. In conclusion, probiotics administration to patients receiving high doses of broad spectrum antibiotics may prevent the occurrence of antibiotic-associated diarrhea. A further study with a larger number is required.

Description

Chotmaihet Thangphaet.

Citation

Jirapinyo P, Densupsoontorn N, Thamonsiri N, Wongarn R. Prevention of antibiotic-associated diarrhea in infants by probiotics. Journal of the Medical Association of Thailand. 2002 Aug; 85 Suppl 2(): S739-42