Urinary symptoms and quality of life changes in Thai women with overactive bladder after tolterodine treatment.
No Thumbnail Available
Date
2005-11-14
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
OBJECTIVES: To study the urinary symptoms and quality of life changes in Thai women with overactive bladder (OAB) after tolterodine treatment.
MATERIAL AND METHOD: Thirty women (aged 30-77 years) diagnosed as having OAB at the Gynecology Clinic, King Chulalongkorn Memorial Hospital from January to April 2004 were included in the present study. Tolterodine 2 mg, twice daily was given. After 8 weeks treatment, changes in micturition diary variables and tolerability were determined. Short form 36 (SF36) questionaires (Thai version) were given before and after 8 weeks of treatment.
RESULTS: At 8 weeks, all micturition per day decreased from 16. 7 +/- 5. 3 to 6. 7 +/- 2.4 times per day. The number of nocturia episodes decreased from 5.4 +/- 4.2 to 1.1 +/- 1.0 times per night. The most common side effect was dry month in 5 cases (16.7%) with 2 cases reporting a moderate degree and 1 case with severe degree. Only one case (3.3%) withdrew from the present study due to a severe dry mouth. The SF-36 scores changed significantly in the domains of physical functioning, role function emotional, social function and mental heath.
CONCLUSION: Tolterodine was well tolerated and its effects improved the quality of life in Thai women with OAB.
Description
Chotmaihet Thangphaet.
Keywords
Citation
Bunyavejchevin S. Urinary symptoms and quality of life changes in Thai women with overactive bladder after tolterodine treatment. Journal of the Medical Association of Thailand. 2005 Nov; 88(11): 1497-501