Post operative penicillin-non-susceptible Streptococcus pneumoniae meningitis and septic shock in a child.

Lumbiganon, Pagakrong; Surakunprapha, Palakorn; Kosalaraksa, Pope; Chaimanee, Prajuab

Post operative penicillin-non-susceptible Streptococcus pneumoniae meningitis and septic shock in a child.

Date

2008-04-18

Authors

Lumbiganon, Pagakrong

Surakunprapha, Palakorn

Kosalaraksa, Pope

Chaimanee, Prajuab

Abstract

The authors describe a one-year-old girl with a fronto-ethmoidal encephalomeningocele who developed wound infection, purulent meningitis and septic shock 5 hours after operation. The patient was treated with intravenous ceftazidime and vancomycin empirically. The cerebrospinal fluid (CSF) and eye discharge grew Streptococcus pneumoniae (S. pneumoniae). The minimal inhibitory concentration (MIC) by E-test of penicillin and cefotaxime were 1.0 and 0.38 ug/ml respectively so the antibiotics were switched to cefotaxime 300 mg/kg/day. She recovered completely after appropriate treatment. Penicillin-non-susceptible S. pneumoniae should be considered as one of the causes of post-operative serious infection of the face and neck in the era of increasing prevalence of penicillin-resistant S. pneumoniae.

Description

Chotmaihet Thangphaet.

Citation

Lumbiganon P, Surakunprapha P, Kosalaraksa P, Chaimanee P. Post operative penicillin-non-susceptible Streptococcus pneumoniae meningitis and septic shock in a child. Journal of the Medical Association of Thailand. 2008 Apr; 91(4): 574-6