Itraconazole in the treatment of cryptococcal meningitis.
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Date
1992-02-01
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Abstract
The results of an open study of the efficacy of oral itraconazole therapy in 8 patients with cryptococcal meningitis are reported. Therapy is monitored by clinical response with culture, indian ink stain and cryptococcal antigen testing of CSF. Four (50%) of eight patients were cured, two (25%) had partial response, and two (25%) failed. One patient had a relapse but responded to retreatment. No toxicity was observed. Itraconazole is, therefore, suggested as a new treatment for cryptococcal meningitis.
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Chotmaihet Thangphaet.
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Citation
Chotmongkol V, Jitpimolmard S. Itraconazole in the treatment of cryptococcal meningitis. Journal of the Medical Association of Thailand. 1992 Feb; 75(2): 85-8