Streptococcal endocarditis treated with two-week antibiotic regimen: preliminary report of a partial oral regimen.

Chayakul, P; Akaravinake, A; Yipintsoi, T

Streptococcal endocarditis treated with two-week antibiotic regimen: preliminary report of a partial oral regimen.

Date

1993-07-01

Authors

Chayakul, P

Akaravinake, A

Yipintsoi, T

Abstract

We reported 18 consecutive patients with penicillin-sensitive streptococcal IE (infective endocarditis). Twelve were successfully treated with a 2-wk course of penicillin G sodium (PGS) and gentamicin, the dosages of which were guided by minimal inhibitory concentration, minimal bactericidal concentration and serum bactericidal titer (SBT), followed by another six who were treated equally successfully with a one week PGS followed by a second week of amoxycillin together with the usual 2 wks of gentamicin. It is believed that oral therapy, after the initial 2-3 days of parenteral antimicrobial, may be adequate for penicillin-sensitive streptococcal IE.

Description

Chotmaihet Thangphaet.

Citation

Chayakul P, Akaravinake A, Yipintsoi T. Streptococcal endocarditis treated with two-week antibiotic regimen: preliminary report of a partial oral regimen. Journal of the Medical Association of Thailand. 1993 Jul; 76(7): 374-9