Sex and seasonal variations of plasma retinol, alpha-tocopherol, and carotenoid concentrations in Japanese dietitians.

Xiang, Jin; Nagaya, Teruo; Huang, Xin-En; Kuriki, Kiyonori; Imaeda, Nahomi; Tokudome, Yuko; Sato, Juichi; Fujiwara, Nakako; Maki, Shinzo; Tokudome, Shinkan

Sex and seasonal variations of plasma retinol, alpha-tocopherol, and carotenoid concentrations in Japanese dietitians.

Date

2008-07-08

Authors

Abstract

AIM: To clarify sex and seasonal variations of plasma antioxidant concentrations among middle-aged Japanese. SUBJECTS AND METHODS: We investigated sex and seasonal variations of plasma antioxidant concentrations, including retinol, alpha-tocopherol, and carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein and lycopene), in 55 middle-aged dietitians (46 women and 9 men) in Aichi Prefecture, Central Japan, who took no supplements from autumn 1996 to summer 1997. Reversed-phase high performance liquid chromatography was used to measure plasma antioxidant concentrations in overnight-fasting blood samples. RESULTS: Plasma levels of alpha-tocopherol, alpha-/beta-carotene, b-cryptoxanthin and lutein were significantly influenced by sex, being significantly higher for women than men in each corresponding season; retinol and lycopene, however, showed no such difference. For women, winter values of alpha-tocopherol, alpha-/beta-carotene, lutein and lycopene were significantly lower than corresponding summer values, and had reached their annual lowest. Retinol failed to show any significant seasonal variation, whereas the winter value of beta-cryptoxanthin had reached its annual highest. For men, beta-cryptoxanthin exhibited significant seasonal changes and was also highest in winter. Winter values of alpha-tocopherol, alpha-/beta-carotene and lycopene were lower compared with other seasons, but not statistically significant, probably due to the small sample size. CONCLUSIONS: The findings indicate that sex and seasonal variations of plasma antioxidant concentrations should be taken into account in nutritional epidemiologic studies.

Description

Asian Pacific Journal of Cancer Prevention.

Citation

Xiang J, Nagaya T, Huang XE, Kuriki K, Imaeda N, Tokudome Y, Sato J, Fujiwara N, Maki S, Tokudome S. Sex and seasonal variations of plasma retinol, alpha-tocopherol, and carotenoid concentrations in Japanese dietitians. Asian Pacific Journal of Cancer Prevention. 2008 Jul-Sep; 9(3): 413-6