Lack of association between Helicobacter pylori and laryngeal carcinoma.
No Thumbnail Available
Date
2008-01-29
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
OBJECTIVE: To survey the role of Helicobacter pylori at the tissue level as a cause of squamous cell carcinoma of the larynx. DESIGN: A case-control study. SETTING: In an Otolaryngology Ward at an academic university. SUBJECTS: Patients with laryngeal cancer as cases and patients with benign laryngeal lesion as controls. MAIN OUTCOME MEASURE: In all subjects, specimens of laryngeal tissue were examined by rapid urease test while histopathologic examination was achieved to detect H. Pylori.
RESULTS: Totally, 44 patients (42 men and 2 women) with squamous cell carcinoma of larynx and 30 patients (24 men and 6 women) with benign laryngeal lesions (polyp, nodule, granuloma) were studied, none of which were infected with the bacterium.
CONCLUSION: Our results did not show H. Pylori infection among patients with laryngeal cancer (SCC) or benign laryngeal lesions. .
Description
Asian Pacific Journal of Cancer Prevention.
Keywords
Citation
Masoud N, Manouchehr K, Najmeh D, Monireh H. Lack of association between Helicobacter pylori and laryngeal carcinoma. Asian Pacific Journal of Cancer Prevention. 2008 Jan-Mar; 9(1): 81-2