Predominant human rotavirus genotype G1P[8] infection in infants and children in Bangkok, Thailand.

Noppornpanth, S; Theamboonlers, A; Poovorawan, Y

Predominant human rotavirus genotype G1P[8] infection in infants and children in Bangkok, Thailand.

Date

2001-03-10

Authors

Noppornpanth, S

Theamboonlers, A

Poovorawan, Y

Abstract

Human rotavirus is the major etiologic agent of infantile diarrhea on a worldwide scale. In this study, rotaviruses were detected by reverse-transcription PCR in 42 of 83 stool specimens from children below the age of 3 years with acute diarrhea in Bangkok, Thailand, between November 1998 and August 1999. G and P types of all samples were characterized by restriction endonuclease analysis (REA) and multiplex PCR typing assay, respectively. Strain G1P[8] (76.1%) was the predominant type, followed by G1P[6] (2.4%). Strain G1 combined with mixed P[8]/P[6] was identified in 2 specimens (4.8%) and 7 untypeable G strains (16.7%) were observed. This information on the circulating G and P combinations should be useful for understanding the epidemiology of human rotavirus in Bangkok, Thailand.

Description

Published by the Allergy and Immunology Society of Thailand.

Citation

Noppornpanth S, Theamboonlers A, Poovorawan Y. Predominant human rotavirus genotype G1P[8] infection in infants and children in Bangkok, Thailand. Asian Pacific Journal of Allergy and Immunology. 2001 Mar; 19(1): 49-53