Immune status in congenital infections by TORCH agents in pregnant Thais.
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Date
1997-06-01
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Abstract
A cross-sectional, sero-epidemiological survey of the prevalence of antibodies to TORCH agents during various stages of gestation revealed an overall rate of 13-15 percent having antibodies to Toxoplasma gondii; 85-87 percent, to rubella ; 79-81 percent, to herpes simplex virus (HSV); 100 percent, to cytomegalovirus (CMV); 82-86 percent, to human herpes virus type 6 (HHV-6); 1-2 percent, to hepatitis C virus (HCV). None of human T lymphotropic virus type I (HTLV-I) antibody was detected, and a prevalence of hepatitis B surface antigen (HBsAg) was 6 percent. Although a tendency was noted towards an increase of antibody detection to each TORCH agent as gestation progressed, a statistically significant increase in antibodies titer and specific IgM antibody was found with regard to CMV. These results suggest an increase in CMV infection or reactivation during pregnancy whereas an increase in the other TORCH infections was not obvious.
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Published by the Allergy and Immunology Society of Thailand.
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Citation
Taechowisan T, Sutthent R, Louisirirotchanakul S, Puthavathana P, Wasi C. Immune status in congenital infections by TORCH agents in pregnant Thais. Asian Pacific Journal of Allergy and Immunology. 1997 Jun; 15(2): 93-7