V3 peptide enzyme immunoassay for serotyping HIV-1 infected pregnant Thais.

Taechowisan, T; Sutthent, R; Louisirirotchanakul, S; Puthavathana, P; Wasi, C

V3 peptide enzyme immunoassay for serotyping HIV-1 infected pregnant Thais.

Date

1996-12-01

Authors

Taechowisan, T

Sutthent, R

Louisirirotchanakul, S

Puthavathana, P

Wasi, C

Abstract

Previous molecular epidemiological studies show that at least 2 subtypes of HIV-1 circulate in Thailand. HIV-1 subtype B or Thai genotype B was associated with an early epidemic and was prevalent in intravenous drug users. Meanwhile, HIV-1 subtype E or Thai genotype A was becoming widespread among heterosexuals. We studied the HIV subtypes of 161 HIV-1 seropositive pregnant women. Of these, 143 pregnant patients (88.8%) tested positive for subtype E alone and 8 women (5.0%) had evidence of infection with subtype B alone. There was serologic evidence of infection with a mixture of subtypes in 7 women while the infecting subtype could not be identified in the remaining 3 women. This result agrees with previous information that subtype E predominates in Thai heterosexuals.

Description

Published by the Allergy and Immunology Society of Thailand.

Citation

Taechowisan T, Sutthent R, Louisirirotchanakul S, Puthavathana P, Wasi C. V3 peptide enzyme immunoassay for serotyping HIV-1 infected pregnant Thais. Asian Pacific Journal of Allergy and Immunology. 1996 Dec; 14(2): 121-3