A dot-ELISA test using monoclonal antibody-purified antigens for the diagnosis of paragonimiasis caused by Paragonimus heterotremus.

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Date
1997-09-30
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Abstract
A dot enzyme-linked immunosorbent assay (dot-ELISA) using antigens purified by monoclonal antibody-affinity chromatography was developed for detecting antibodies to Paragonimus heterotremus in four groups of subjects. They consisted of 30 patients with P. heterotremus infection, 93 patients with other parasitic infections, 18 patients with pulmonary tuberculosis and 30 normal, healthy controls. Sensitivity, specificity, as well as positive and negative predictive values of the test were 100, 97, 88, and 100%, respectively.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Citation
Maleewong W, Intapan PM, Wongkham C, Pajongthanasaris M, Morakote N, Tapchaisri P, Chaicumpa W. A dot-ELISA test using monoclonal antibody-purified antigens for the diagnosis of paragonimiasis caused by Paragonimus heterotremus. The Southeast Asian Journal of Tropical Medicine and Public Health. 1997 Sep; 28(3): 621-3