Pulmonary artery obstruction in thalassaemia.
No Thumbnail Available
Date
1980-12-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A new feature has been encountered in review of a large species of autopsy materials of beta-thalassaemia/Hb E disease. Among 43 patients pulmonary arterial obstructive lesions were found in 19 (44%), of which 17 were splenectomised cases. The pulmonary arterial thromboembolism may have been due to circulating platelet aggregates. This newly discovered pathology may be an additional factor contributing toward dyspnoea and heart failure in thalassaemia besides anaemia and cardiac iron deposition. If it is proven that this pulmonary arterial thromboembolism is indeed due to circulating platelet aggregates, preventive measure by administration of drugs reducing platelet aggregation such as aspirin and Persantin may be indicated, especially after splenectomy.
Description
The Southeast Asian Journal of Tropical Medicine and Public Health.
Keywords
Citation
Sonakul D, Pacharee P, Laohapand T, Fucharoen S, Wasi P. Pulmonary artery obstruction in thalassaemia. The Southeast Asian Journal of Tropical Medicine and Public Health. 1980 Dec; 11(4): 516-23