Toxoplasma antibody prevalence in Nepalese pregnant women and women with bad obstetric history.
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Date
1998-12-20
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Abstract
Sera from randomly selected 345 pregnant Nepalese women aged 16-36 years and 13 women with bad obstetric history (BOH) were tested for the presence of Toxoplasma antibodies using microlatex agglutination (MLA) and ELISA methods. The overall prevalence was 55.4% (191/345). Prevalence was slightly higher (59.0%) in older age-group (27-36 years) compared with younger age-group (16-26 years) (52.2%). No significant difference in antibody prevalence in women belonging to two different ethnic-groups (Tibeto-Burmans 57.8%, Indo-Aryans 52.7%) was observed (p>0.05). MLA antibody titer ranged from 1:16 to 1:2,048. Over three-fourth of the women showed either high (1:510 or over) or low (1:16 or 1:32) antibody titer. Three percent (6/191) of MLA antibody positive subjects had Toxoplasma IgM antibodies by IgM-ELISA. All six IgM antibody positive pregnant women had MLA antibody titer of over 1:510. Of the total 13 women with BOH, 5 (38.5%) had Toxoplasma antibodies of which 2 (40.0%) were positive for Toxoplasma-IgM antibodies.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Rai SK, Shibata H, Sumi K, Rai G, Rai N, Manandhar R, Gurung G, Ono K, Uga S, Matsuoka A, Shrestha HG, Matsumura T. Toxoplasma antibody prevalence in Nepalese pregnant women and women with bad obstetric history. The Southeast Asian Journal of Tropical Medicine and Public Health. 1998 Dec; 29(4): 739-43