Growth response in Turner syndrome with recombinant human growth hormone therapy.
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Date
1995-03-01
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Abstract
Ten Turner syndrome girls whose mean age was 10.9 +/- 2.7 years were treated with recombinant human growth hormone (rhGH), dose 0.6 U/kg/week. Five of them had classical 45, XO karyotype. The mean height velocity increased from 2.8 +/- 1.3 cm/year before treatment to 6.1 +/- 2.06 cm/year after treatment for a period of 1.4 years. The response of treatment correlated well with pretreatment height velocity (<3 cm/year) but not with karyotype. However, the response has been decreasing and an increased dose after the first year of treatment is recommended.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Citation
Tuchinda C, Angsusingha K, Punnakanta L, Likitmaskul S, Wacharasindhu S, Tuanakitcharu K, Pitukcheewanont P. Growth response in Turner syndrome with recombinant human growth hormone therapy. The Southeast Asian Journal of Tropical Medicine and Public Health. 1995 ; 26 Suppl 1(): 142-5