Serologic detection of Toxoplasma gondii infection in Rattus spp collected from three different sites in Dasmariñas, Cavite, Philippines.
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2005-11-28
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Abstract
Acute and chronic cases of toxoplasmosis in Rattus norvegicus and Rattus rattus mindanensis caught in agricultural, commercial and residential sites in Dasmariñas, Cavite, Philippines were determined serologically. Fifty-eight percent of R. norvegicus and 42.0% of R. r. mindanensis were positive for anti-T. gondii antibodies (Abs). Infection was higher in male rats, and those caught in the commercial site had 100.0% seropositivity. Thirty percent of the R. norvegicus and 51.0% R. rattus mindanensis had acute infection, with 1:64-1:128 Abs titer. Seventy percent of the R. norvegicus and 49.0% of R. rattus mindanensis were chronically-infected with Abs titer 1:256-1:2048 and 1:256-1024, respectively. The association between the presence of infection with the rat gender and species and their collection sites was insignificant (p>0.05). In a related study, however, mice experimentally-inoculated brain tissue homogenate obtained from chronically-infected Rattus spp, manifested differences in the onset as well as, severity of infection which was histopathologically evaluated, suggestive of a possible difference in T. gondii parasite strain(s) infecting different rat populations.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Salibay CC, Claveria FG. Serologic detection of Toxoplasma gondii infection in Rattus spp collected from three different sites in Dasmariñas, Cavite, Philippines. The Southeast Asian Journal of Tropical Medicine and Public Health. 2005 ; 36 Suppl 4(): 46-9