Effects of antibody to Vibrio cholerae El Tor hemolysin on pathological changes of the intestines in cholera.

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Date
1980-06-01
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Abstract
Pathological abnormalities of the infant mouse small intestines were evident after V.cholerae El Tor, Ogawa, infection. These were revealed by an enteritis manifested by mononuclear cells containing inflammatory exudate, intervillous blood capillary congestion, marked increase in goblet cells, desquamation of epithelium and diapedesis of cells. Mice received V.cholerae pretreated with high concentration of antihemolysin, though developed diarrhea, had marked decrease in pathological severity. The less amount of the antibodies the more pathological changes were found.
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The Southeast Asian Journal of Tropical Medicine and Public Health.
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Samrejrongroj P, Chaicumpa W, Riganti M. Effects of antibody to Vibrio cholerae El Tor hemolysin on pathological changes of the intestines in cholera. The Southeast Asian Journal of Tropical Medicine and Public Health. 1980 Jun; 11(2): 262-6