Thymic histology in myasthenia gravis.

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Date
1992-07-01
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Abstract
Histological features of resected thymuses of 18 patients with myasthenia gravis were evaluated. Thymoma were seen in 16.6% of the patients. In the non-thymomatous group, thymic hyperplasia with follicle formation was seen in 33.3%, involuted thymus with occasional lymphoid follicle formation in 11.1%, thymitis with B cell infiltration in 16.6%, involuted thymus in 11.1% and normal thymus in 11.1% of patients. Immuno-histological staining for B and T lymphocytes delineated the group labelled as thymitis with B cell infiltration. Mast cell and eosinophils were frequently seen in thymuses with thymic hyperplasia with follicle formation and thymitis with B cell infiltration. Thymic hyperplasia with follicle formation was more frequent in young patients and these patients had better prognosis.
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Malhotra V, Tatke M, Khanna SK, Gondal R. Thymic histology in myasthenia gravis. The Indian Journal of Chest Diseases & Allied Sciences. 1992 Jul-Sep; 34(3): 117-21
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https://imsear.searo.who.int/handle/123456789/30245
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Indian Journal of Chest Diseases & Allied Sciences