Cephalosporin acylases: enzyme production, structure and application in the production of 7-ACA.
No Thumbnail Available
Date
1993-02-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Cephalosporin acylases have application in the production of 7-aminocephalosporanic acid which forms a key raw material for the preparation of semisynthetic injectable cephalosporins. The enzymes are of industrial importance and hyperproducing genetically engineered strains have been constructed. Different aspects of these enzymes such as subunit structure, post translational modification, primary structure, substrate specificity and their importance in pharmaceutical industry are discussed.
Description
35 references.
Keywords
Citation
Kumar KK, Sudhakaran V, Deshpande BS, Ambedkar SS, Shewale JG. Cephalosporin acylases: enzyme production, structure and application in the production of 7-ACA. Hindustan Antibiotics Bulletin. 1993 Feb-May; 35(1-2): 111-25