Immunofluorescent microscopic findings in glomerulonephritis.
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1997-12-11
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Abstract
Histopathology and direct immunofluorescence (DIF) microscopy were performed on renal biopsy specimens of 60 clinically suspected cases of glomerulonephritis (GN). Histopathological diagnosis was obtained in 44 (73.3%) cases and immune complex deposition were detected by DIF in 28 (46.7%) cases. Immune complex deposition were observed in all cases of membranous GN, systemic lupus erythematosus (SLE), and rapidly progressive GN (RPGN), most of the cases of diffuse proliferative GN (2 out of 3) mesangioproliferative GN (12 out of 15) and focal glomeruloscleros is (3 out of 5 cases). No immune deposits were observed in minimal change GN, chronic GN, and diabetic nephropathy. Histopathological diagnosis was not obtained in 16 (26.7%) cases, 3 (5%) of which showed immune complex deposition by DIF. Anti-GBM nephritis was demonstrated in one (3.6%) case, the rest were immune complex nephritis.
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Bangladesh Medical Research Council Bulletin.
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Tabassum S, Rahman KM, Mamun KZ, Ahmed AN, Islam KM, Rahman H. Immunofluorescent microscopic findings in glomerulonephritis. Bangladesh Medical Research Council Bulletin. 1997 Dec; 23(3): 77-81