Age-related cataract - Prevalence, epidemiological pattern and emerging risk factors in a cross-sectional study from Central India

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Date
2023-05
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Publisher
All India Ophthalmological Society
Abstract
Purpose: To study the epidemiological pattern, prevalence, types, and correlates of age?related cataracts in a tertiary care center in central India. Methods: This hospital?based single?center cross?sectional study was conducted on 2,621 patients diagnosed with cataracts for 3 years. Data pertaining to demography, socio?economic profile, cataract grading, cataract types, and associated risk factors were evaluated. Statistical analysis using unadjusted odds ratio (OR) and multivariate logistic regression was performed, with P-value <0.05 considered significant with the power of the study being 95%. Results: The commonest age group affected was 60–79 years, closely followed by the 40–59 years age group. The prevalence of nuclear sclerosis (NS), cortical (CC), and posterior subcapsular cataract (PSC) was found to be 65.2% (3,418), 24.6% (1,289), and 43.4% (2,276), respectively. Among mixed cataracts, (NS + PSC) had the highest prevalence of 39.8%. Smokers were found to have 1.17 times higher odds of developing NS than non?smokers. Diabetics had 1.12 times higher odds of developing NS cataracts and 1.04 times higher odds of developing CC. Patients with hypertension showed 1.27 times higher odds of developing NS and 1.32 times higher odds of developing CC. Conclusion: The prevalence of cataracts in the pre?senile age group (<60 years) was found to have increased significantly (35.7%). A higher prevalence of PSC (43.4%) was found in studied subjects, as compared to the data of previous studies. Smoking, diabetes, and hypertension were found to have a positive association with a higher prevalence of cataracts.
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Keywords
Age?related cataract, prevalence of cataracts, risk factors of cataract
Citation
Sarkar Deepayan, Sharma Ria, Singh Priti, Verma Vidhya, Karkhur Samendra, Verma Sunil, Soni Deepak, Sharma Bhavana. Age-related cataract - Prevalence, epidemiological pattern and emerging risk factors in a cross-sectional study from Central India. Indian Journal of Ophthalmology. 2023 May; 71(5): 1905-1912