Rasch development and validation of the “Medellín Dry Eye Inventory” (ME·Dry), an instrument to measure multidimensional quality of life compromise in patients with dry eye disease

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Date
2023-04
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Publisher
All India Ophthalmological Society
Abstract
Purpose: Dry eye disease (DED) is a common condition that affects the quality of life. There is a great need for better?developed scales that comply with Rasch model requirements. Methods: Prospective study including patients with DED. A series of focus groups were performed to determine the best items to be included. A Rasch modeling methodology was used to validate the Medellín Dry Eye Inventory (ME·Dry). After iterative analysis and scale modification, a final version of the scale was attained which complied with the Rasch analysis expectations. Correlation between the different subscales of the ME·Dry and the Ocular Surface Disease Index (OSDI) was evaluated through Spearman correlation. Results: A total of 166 patients with DED were included. Rasch modeling demonstrated an excellent behavior for the ME·Dry, including four subscales: Symptoms, Triggers, Activity Limitation, and Emotional Compromise. Infit and Outfit parameters were all between 0.50 and 1.50, with excellent category utilization. Person and item separation and reliability were excellent for all subscales. There was a need for a category collapsing for the Emotional Compromise subscale. There was a strong correlation between the different subscales of the ME·Dry except for the Emotional Compromise subscale, which seems to be independent. Conclusion: The ME·Dry is a reliable scale, complying with the Rasch model expectations, that allows for a reliable measurement of quality of life compromise in patients with DED. Emotional compromise secondary to DED does not seem to correlate with disease severity as assessed by the other quality?of?life subscales.
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Keywords
Dry eye disease, ocular surface disease, quality of life
Citation
Balparda Kepa, Herrera-Chalarca Tatiana, Cardozo-Dávila Ximena, Pacheco Maria A, Godin Fernando, Nicholls-Molina María A. Rasch development and validation of the “Medellín Dry Eye Inventory” (ME·Dry), an instrument to measure multidimensional quality of life compromise in patients with dry eye disease. Indian Journal of Ophthalmology. 2023 Apr; 71(4): 1432-1440