Red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
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Date
2022-08
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
Purpose: The purpose of this study was to assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliation glaucoma (PEXG), and to compare their RDW values with healthy controls. Methods: 40 patients with PEX, 40 with PEXG, and 80 control subjects were enrolled in this study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within one hour of blood collection. Results: RDW levels were significantly higher in patients with PEX and PEXG than in controls (P = 0.027 and P < 0.001, respectively). Furthermore, a significant difference was found in RDW values between PEXG and PEX groups (P = 0.016). RDW levels were gradually increased from control group to PEXG group (P < 0.001). Multivariate logistic regression analysis revealed that RDW was independently associated with the presence of PEX/PEXG (odds ratio 1.765, 95% confidence interval (CI) 1.095–2.867, P = 0.013). Conclusion: We conclude that RDW may be a useful marker for predicting the presence of PEX and progression to PEXG.
Description
Keywords
Inflammation, neutrophil, pseudoexfoliation, red cell distribution width
Citation
Bashir Jasiya, Beg Danish T, Beigh Arshid A, Wani Ejaz A. Red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Indian Journal of Ophthalmology. 2022 Aug; 70(8): 2902-2905