Outcomes and favourable prognostic factors in patients of phacomorphic and phacolytic glaucoma managed by manual small-incision cataract surgery: A retrospective study

Abstract
Purpose: To evaluate the outcomes and identify favorable prognostic factors in patients of phacomorphic (PMG) and phacolytic glaucoma (PLG) managed by manual small?incision cataract surgery (MSICS). Methods: The medical records of patients with PMG/PLG who had undergone MSICS in a tertiary eye hospital between September 2014 and August 2018 were retrospectively reviewed. Regression analyses were conducted to identify the predictors associated with intraoperative or postoperative complications and a favorable final outcome at 1 month, namely, a best?corrected visual acuity (BCVA) of 6/18 or better and an intraocular pressure (IOP) of <21 mm Hg. P < 0.05 was considered statistically significant. Results: The records of 209 patients with PMG and 279 patients with PLG were eligible for the review. The mean preoperative IOP for PMG and PLG were 43.15 � 12.9 and 40.05 � 12.0 mm Hg, respectively (P = 0.006). A younger age (<60 years) was associated with a lower risk of severe postoperative inflammation in both PMG and PLG [OR = 0.45 (0.21�99); P = 0.047 and OR = 0.44 (0.23�83); P = 0.011, respectively]. There was no significant difference in the final mean logMAR BCVA (P = 0.21) and IOP (P = 0.36) in the two groups. The likelihood of a final IOP of <21 mm Hg was significant for symptoms less than a week [OR = 3.52 (1.2�.2); P = 0.02] in PMG and for absence of vitreous disturbance [OR = 35.0 (3.8�5.7); P = 0.002] in PLG. A BCVA of 6/18 or better was strongly associated with symptoms for less than a week [OR = 1.58 (1.0�4); P = 0.043] and absence of vitreous disturbance [OR = 23.53 (5.1�8.0); P < 0.001]. Conclusion: Early diagnosis and management can translate to good outcomes in PMG and PLG.
Description
Keywords
Manual small?incision cataract surgery, phacolytic glaucoma, phacomorphic glaucoma
Citation
Chandrashekharan Shivkumar, Chakrabarty Sabyasachi, Tanwar Meghana, Madhuvarasu Bharadwaja, Uduman Mohammed Sithiq, Ramakrishnan Rengappa. Outcomes and favourable prognostic factors in patients of phacomorphic and phacolytic glaucoma managed by manual small-incision cataract surgery: A retrospective study. Indian Journal of Ophthalmology. 2022 Apr; 70(4): 1216-1221