Secondary developmental glaucoma in eyes with congenital aphakia
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Date
2022-03
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
Purpose: To describe the clinical spectrum and management of glaucoma in congenital aphakia. Methods: The demographics and clinical spectrum of eyes with congenital aphakia with and without glaucoma were compared, and management outcomes of congenital aphakia cases with glaucoma were studied retrospectively between April 2000 and June 2020. Results: There were a total of 168 eyes (84 subjects) with a diagnosis of congenital aphakia, of which 29 eyes of 18 subjects were diagnosed with glaucoma. Corneal opacity was the presenting complaint in 26/29 eyes with glaucoma and 139/139 eyes without glaucoma. The (interquartile range (IQR)) horizontal corneal diameter was 10.5mm (IQR, 9.0?12.5) and 8mm (IQR, 5?10) in eyes with and without glaucoma (P = 0.01), respectively. The median (IQR) axial length was 17.5mm (IQR, 13.5?19.5) and 15mm (IQR, 14?16) mm in eyes with and without glaucoma (P = 0.03), respectively. Nineteen eyes with glaucoma had adequate intraocular pressure (IOP) control with one medication. Three eyes underwent transscleral diode cyclophotocoagulation and maintained IOP without medications. Three eyes underwent trabeculectomy and trabeculotomy, trabeculectomy followed by penetrating keratoplasty, and trabeculectomy, respectively, of which two eyes became phthisical. At the last follow?up, the median (IQR) IOP was 14 mm Hg (IQR, 14?17) Hg. The median (IQR) follow?up duration was 4.53 months (IQR, 2.03? 48.06). Conclusion: One?fifth of the eyes with congenital aphakia had secondary developmental glaucoma. The corneal diameter and axial lengths were higher in the eyes with glaucoma compared to eyes without glaucoma. Medical management is the preferred short?term mode of IOP control. Transscleral cyclophotocoagulation may be preferred over surgical intervention.
Description
Keywords
Clinical spectrum of glaucoma, congenital aphakia, secondary developmental glaucoma
Citation
Ramyashri S, Mohamed Ashik, Chaurasia Sunita, Senthil Sirisha. Secondary developmental glaucoma in eyes with congenital aphakia. Indian Journal of Ophthalmology. 2022 Mar; 70(3): 834-838