Significance of Laboratory Markers in Predicting the Severity of COVID-19 in the Central Reserve Police Force Front-line Workers with a Review of Literature
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Date
2022-12
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Publisher
Wolters Kluwer – Medknow
Abstract
COVID-19 disease has variable clinical presentations, ranging from asymptomatic to mild symptoms to severe manifestation with pneumonia, acute respiratory distress syndrome, septic shock, disseminated intravascular coagulation, and/or multiple organ failure. The real?time reverse transcription–polymerase chain reaction is gold standard test for severe acute respiratory syndrome?coronavirus?2 detection. In the present study, we aimed to predict the significance of various hematological and biochemical markers for early identification of complications and assessing the severity of the disease. A total of cases were divided into two study groups, namely, severe and nonsevere based on clinical presentation. Out of 210 cases, 186 (88.5%) cases were nonsevere and 24 (11.5%) cases were severe. Among various hematological and biochemical markers studied, hemoglobin, total leukocyte count, neutrophil count, lymphocyte count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, albumin, lactate dehydrogenase, C?reactive protein, ferritin, D?dimer, and interleukin?6 are found to have P < 0.05 and significantly correlated with the severity of disease.
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Keywords
COVID?19, Central Reserve Police Force, severe acute respiratory syndrome?coronavirus?2, severe
Citation
Reddy CH, Achari PK, Nisha B, Radha AR.. Significance of Laboratory Markers in Predicting the Severity of COVID-19 in the Central Reserve Police Force Front-line Workers with a Review of Literature. Indian Journal of Public Health. 2022 Dec; 66(4): 512-515