Myoglobin cast nephropathy following multiple bee stings
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Date
2023-03
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Publisher
Wolters Kluwer - Medknow
Abstract
Bee stings usually result in mild allergic reactions; however, mass envenomation can cause severe complications such as rhabdomyolysis, hemolysis, shock, or multi-organ damage. Rhabdomyolysis can result in acute renal failure either by tubular obstruction by myoglobin casts or by direct cytotoxic injury. We present a case of a 12-year-old female child who presented with sudden onset anuria and hypertension following mass envenomation by bees. A renal biopsy was performed, the microscopic evaluation of which revealed tubular injury, with associated intratubular pigmented casts. The casts stained positive for myoglobin immunohistochemical stain, thus confirming a diagnosis of myoglobin cast nephropathy. The patient was given IV steroids and underwent seven sessions of hemodialysis, following which there was complete recovery of renal function.
Description
Keywords
Acute renal failure, bee-sting, pigmented casts, rhabdomyolysis
Citation
Madireddy N, Swain M, Yalamarty R.. Myoglobin cast nephropathy following multiple bee stings. Indian Journal of Pathology & Microbiology. 2023 Mar; 66(1): 177-179