Clinician's dilemma: Naproxen-induced liver injury
Loading...
Date
2023-03
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer - Medknow
Abstract
Naproxen is a widely used nonsteroidal anti-inflammatory drug (NSAID) in pediatric population, used for mild-to-moderate pains, arthritis, and other immune-mediated disorders. It rarely causes clinically apparent liver injury in the adult population taking high doses of the drug over a prolonged period and is reported even rarer in pediatric population. We present a case of drug-induced liver injury (DILI) in a 13-year-old girl taking naproxen in therapeutic doses for juvenile rheumatoid arthritis. There was a complete recovery of liver function following discontinuation of naproxen therapy.
Description
Keywords
DILI, drug-induced liver injury, juvenile rheumatoid arthritis, naproxen, nonsteroidal anti-inflammatory drug
Citation
Sharma S, Sharma A, Surya M, Guleria S, Bansal N.. Clinician's dilemma: Naproxen-induced liver injury. Indian Journal of Pathology & Microbiology. 2023 Mar; 66(1): 168-170