Myeloid sarcoma presenting as nasopharyngeal mass: A rare clinicopathological scenario

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Date
2023-03
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer - Medknow
Abstract
Myeloid sarcoma (MS) is considered as an extramedullary manifestation of acute myeloid leukemia (AML) with or without concurrent AML. It can present at any age and any site, however, nasopharynx being an extremely rare site of manifestation. MS may precede AML by weeks, months or years, thereby necessitating an early diagnosis and timely intervention and treatment. We report a case of MS in a young female who presented with nasal obstruction and epistaxis for 3 months. The present case also highlights the significance of judicious use of immunohistochemistry panel while dealing with a hematolymphoid neoplasm devoid of expression of B-cell or T cell specific markers in head and neck region.
Description
Keywords
Hematolymphoid malignancy, myeloid sarcoma, nasopharynx
Citation
Diwan H, Pasricha S, Jajodia A, Gupta G, Agarwal M, Mehta A.. Myeloid sarcoma presenting as nasopharyngeal mass: A rare clinicopathological scenario. Indian Journal of Pathology & Microbiology. 2023 Mar; 66(1): 162-164