Predictors of dementia amongst newly diagnosed non-valvular atrial fibrillation patients

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Date
2022-12
Journal Title
Journal ISSN
Volume Title
Publisher
Cardiological Society of India
Abstract
Atrial fibrillation (AF) confers a 2-to-3-fold increased risk of developing cognitive dysfunction and dementia, independent of age and past stroke. The purpose of study was to identify risk factors for developing dementia amongst AF patients in India. This was a single-centre, prospective, observational study wherein recently diagnosed, treatment naïve, persistent non-valvular AF patients were enrolled. All patients were screened for dementia using the Mini-Mental state exam. Amongst a total of 108 patients enrolled, 40 (37%) had dementia. The most common cognitive deficits were in attention and calculation followed by memory deficits. Factors independently contributing to dementia were advanced age, female sex, presence of diabetes, elevated pulmonary artery pressures and a lower serum albumin.
Description
Keywords
Atrial fibrillation, Dementia, Cognitive decline
Citation
Batta Akash, Sharma Yash Paul, Hatwal Juniali, Panda Prashant, Kumar Budumuri Gautam Vinay, Bhogal Sukhdeep . Predictors of dementia amongst newly diagnosed non-valvular atrial fibrillation patients. Indian Heart Journal. 2022 Dec; 74(6): 505-509