Evaluation of Early Post-Operative Morbidity and Mortality Following Resectional Surgery of Colorectal Cancer
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Date
2022-10
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Scholars Publisher
Abstract
Background: Colorectal cancer is one of the most occurring malignancies all over the world. The only curative option is surgery and post-operative morbidity and mortality should be minimized to improve outcome. Surgical resection is still the principal treatment for colorectal cancer. To evaluate early post-operative morbidity and mortality following resectional surgery of colorectal cancer.Material & Methods:This longitudinal type of descriptive study was conducted at the department of Surgery, Rangpur Medical College Hospital after ethical approval between July’ 2019 to June ‘2020. Informed written consent was obtained from the participants after explanation of the nature and purpose of the study. A total 33 patients were taken as study population. Meticulous history taking and thorough physical examination were done of all patients. Thirty day’s postoperative mortality and morbidity was evaluated on the basis of pre-existing co-morbidities and surgical procedure with attendant complications. Appropriate statistical test was performed. Data was analyzed through SPSS version 22.0.Results:More than one third (35.3%) patients belonged to age >50 years in group I and 25.0% in group II. More than half (58.8%) patients were female in group I and 5(31.2%) in group II. Diabetes mellitus were found in 41.2% patients, 47.05% patients were active smoker in group I and 6.25% in group II. Hypertension was found in 52.9% patients. More than half (52.9%) patients had stage II in group I and 68.8% in group II. By ASA, 23.5% patients had normal healthy in group I and 68.8% in group II. 47.1% patients had mild systemic disease in group I and 31.2% in group II, 27.4% patients had severe systemic disease in group I. By intra-operative time, majority (82.4%) patients had more than 2 hours in group I and 5(31.2%) in group II. More than half (52.9%) patients had intra operative blood loss in group I and 6(37.5%) in group II. 47.1% patients developed wound infection in first follow up, 23.5% in second follow-up and 29.4% in third follow-up. Majority (78.6%) patients belonged to serum albumin ?3.5 in patients with morbidity and 33.3% in mortality.Conclusion:Diabetes mellitus and hypertension were predominant comorbidities and associated with poor surgical outcome. Active smoking had also negative impact on post-operative complications. Majority patients showed low preoperative serum albumin ?3.5 with increased morbidity and mortality. It could be reasonably imparting an insight for convincing that hard data should supplant much of the foregoing speculation by colorectal cancer surveillance program.
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Keywords
Colorectal cancer, Malignancies, Morbidity, Mortality, Resectional surgery.
Citation
Methila Meherun Khan, Islam Md. Raisul, Khan Mahfuz Alam, Roy Bimal Chandra Roy. Evaluation of Early Post-Operative Morbidity and Mortality Following Resectional Surgery of Colorectal Cancer. Annals of International Medical and Dental Research. 2022 Oct; 8(5): 229-243